help! MS1 signal drop in QE MS
Posted: Mon Sep 21, 2015 6:44 pm
Hi,
I recently got a problem with my Q exective MS, the MS1 signal suddenly droped from 10E9 to 10E7, although background signal also droped, and the spectra looks normal too. The MS2 looked good too with 10E7 signal. I searched the data, and still gives me lots of proteins IDs. I switched from nanospray to regular HESI sourse, and the signal is still low. Does anyone here have a clue about this problem?
thank you!
SunSun
I recently got a problem with my Q exective MS, the MS1 signal suddenly droped from 10E9 to 10E7, although background signal also droped, and the spectra looks normal too. The MS2 looked good too with 10E7 signal. I searched the data, and still gives me lots of proteins IDs. I switched from nanospray to regular HESI sourse, and the signal is still low. Does anyone here have a clue about this problem?
thank you!
SunSun