We recently did an interesting study looking at non-specific binding of IgG to a COOH sensor in a surface plasmon resonance instrument. We looked at the effect of pH, salt, BSA, and Tween and how each of these impacted the level of non-specific binding. If anyone is aware of any similar studies we would love to hear about them. The results of ours is quite interesting.
The blog post and full article can be found here.
Any feedback is much appreciated and please reach out if you have any questions.
Whether you are building your own mass spec, modifying an existing one, or just need help with instrument settings post about it in here.
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